副教授
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陈小川
发布时间:2020年09月06日 19:16  作者:本站编辑     来源:本站原创   浏览次数:

陈小川,男,重庆市人,副教授,硕士生导师

一、学习工作经历

2020.07⁓至今,西南大学,皇冠买足球的官网,副教授、硕导

2012.10⁓2020.07,西南大学,动物科技学院,历任讲师、副教授、硕导

2009.06⁓2012.05,美国亚利桑那大学,动物科学专业,博士

2007.09⁓2009.05,美国亚利桑那大学,动物科学专业,硕士

2003.09⁓2007.06,西南大学,水产养殖专业,农学学士

二、研究方向及成果

主要采用山羊、大鼠动物模型,致力于环境诱导的子宫不良内环境对胎儿后期发育及后天生长的内分泌和代谢调控紊乱研究。

主持科研项目

2022,基于多模型视觉识别的畜牧养殖的人工智能平台与大数据服务,横向项目(项目编号4412200218)

2016⁓2019,持续高浓度去甲肾上腺素对胎羊胰岛素分泌的影响和机制研究,国家自然科学基金(项目编号31602021)

2015⁓2017,长期高浓度去甲肾上腺素对绵羊胎儿胰岛素分泌调控的影响,重庆市科委前沿与创新(项目编号CSTC2014JCYJA80036)

2014⁓2016,中央高校基本科研业务费(项目编号XDJK2014C020)

2013⁓2017,西南大学博士基金(项目编号20710916)

参与科研项目

2020,巫溪县老鹰茶、生猪产业技术创新研究与应用—巫溪县天元乡象坪村生猪养殖产业示范园建设,横向项目(项目编号4312000351)

2016-2020,乳酸菌SL001对AD模型小鼠胆固醇代谢及Aβ生成的影响及作用机制研究,国家自然科学基金(项目编号31670123)

2016-2020,温和型热应激下胰岛素信号系统在公猪睾丸支持细胞乳酸生成中的分子机制,国家自然科学基金(项目编号31672624)

2013-2015,草食动物种质创新与健康养殖,重庆市科委(项目编号KJTD201334)

代表性论文

1.Liu T, Li R, Luo N, Lou P, Limesand SW, Yang Y, Zhao Y, Chen X*. Hepatic Lipid Accumulation and Dysregulation Associate with Enhanced Reactive Oxygen Species and Pro-Inflammatory Cytokine in Low-Birth-Weight Goats. Animals. 2022; 12(6):766. https://doi.org/10.3390/ani12060766

2.Li R, Huang H, Limesand SW, Chen X*. Pancreatic Islets Exhibit Dysregulated Adaptation of Insulin Secretion after Chronic Epinephrine Exposure. Current Issues in Molecular Biology. 2021; 43(1):240-250. https://doi.org/10.3390/cimb43010020

3.Zhanfu Li, Xiaochuan Chen, Yongjun Chen, Weilong Li, Qifeng Feng, Haodi Zhang, Xianzhi Huang, Li Luo. Effects of dietary mulberry leaf extract on the growth, gastrointestinal, hepatic functions of Chinese giant salamander (Andrias davidianus). Aquaculture Research. 2020 April. 51(6). DOI: 10.1111/are.14639

4.Luo N, Wang J, Hu Y, Zhao Z, Zhao Y, Chen X*. Cold and heat climatic variations reduce indigenous goat birth weight and enhance pre-weaning mortality in subtropical monsoon region of China. Trop Anim Health Prod. 2020 May;52(3):1385-1394. doi: 10.1007/s11250-019-02142-3.

5.Camacho LE, Chen X, Hay WW Jr, Limesand SW. Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction. Am J Physiol Regul Integr Comp Physiol. 2017 Aug 1;313(2):R101-R109.

6.Chen X, Kelly AC, Yates DT, Macko AR, Lynch RM, Limesand SW. Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine. J Endocrinology. 2017 Feb;232(2):285-295. (影响因子 4.706)

7.Macko AR, Yates DT, Chen X, Shelton LA, Kelly AC, Davis MA, Camacho LE, Anderson MJ, Limesand SW. Adrenal Demedullation and Oxygen Supplementation Independently Increase Glucose-Stimulated Insulin Concentrations in Fetal Sheep with Intrauterine Growth Restriction. Endocrinology. 2016 May;157(5):2104-15.

8.Chen X (陈小川), Green AS, Macko AR, Yates DT, Kelly AC, Limesand SW*. Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep. Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E58-64. doi: 10.1152/ajpendo.00517. (影响因子 4.142)

9.Macko AR, Yates DT, Chen X, Green AS, Kelly AC, Brown LD, Limesand SW*. Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation. J Dev Orig Health Dis. 2013 Oct 1;4(5).

10.Yates DT, Macko AR, Chen X, Green AS, Kelly AC, Anderson MJ, Fowden AL, Limesand SW*. Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep. The Journal of Physiology. 2012: 590(Pt 21):5439-47.

11.Yates DT, Macko AR, Nearing M, Chen X, Rhoads RP, Limesand SW*. Developmental programming in response to intrauterine growth restriction impairs myoblast function and skeletal muscle metabolism. Journal of Pregnancy. 2012:631038.

12.Chen X, Rozance PJ, Hay WW Jr, Limesand SW*. Insulin-like Growth Factor and Fibroblast Growth Factor Expression Profiles in Growth Restricted Fetal Sheep Pancreas. Experimental Biology and Medicine. 2012: 237(5):524-9. (影响因子 2.688)

13.Green AS, Macko AR, Rozance PJ, Yates DT, Chen X (陈小川), Hay WW Jr, Limesand SW*. Characterization of glucose-insulin responsiveness and impact of fetal number and gender on insulin response in the sheep fetus. American Journal of Physiology Endocrinology and Metabolism. 2011: 300(5), E817-823.

14.Chen X, Fahy AL, Green AS, Anderson MJ, Rhoads Jr RP, Limesand SW*. β2-Adrenergic Receptor Desensitization in Perirenal Adipose Tissue in Fetuses and Lambs with Placental Insufficiency-induced Intrauterine Growth Restriction. The Journal of Physiology. 2010: 588(Pt 18):3539-49. (影响因子 4.739)

15.Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW*. Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction. American Journal of Physiology Endocrinology and Metabolism. 2010: 298, E770-778.

16.Zheng K, Chen X, Li Y. Molecular Cloning, Sequence Analysis, and Tissue Expression of Insulin-like Growth Factor-I from Chinese sucker Myxocyprinus asiaticus Bleeker, J, Chinese Journal of Zoology, 2007, 42(2): 39-45. [Chinese].

三、社会兼职

2020⁓2022,重庆市巫溪县凤凰,科技特派员

2018⁓2020,重庆市巫溪县红池坝镇九坪村,科技特派员

2017.09⁓至今,中国畜牧兽医学会动物生理生化分会,理事会理事

2015.12⁓至今,重庆市生物化学与分子生物学会,理事会理事

2014⁓2016,重庆市奉节县鑫鼎农业有限公司,科技特派员

2014.06⁓至今,重庆市科技局,科技特派员

四、学生培养

指导学生创新训练项目

2013⁓2016,王小巧、汤琦、牟烨

2015⁓2018,施磊、代琴芳、郑璐

2017⁓2021,杨丁凡、王琦、武嘉远

部分毕业生去向

王小巧,2016,保送中国农业科学院,硕士研究生

汤琦,2016,保送西南大学,硕士研究生

罗玉茹,2016,考入西北农林科技大学,硕士研究生;2020,考入西安交大,博士研究生

胡苏,2017,考入德国德累斯顿工业大学(Dresden University of Technology),硕士研究生

楼鹏,2019,保送四川大学,硕士研究生

李睿,2020,第四军医大学,科研助理

专利

家畜造瘘用手术台,授权公告号CN 211962266 U,发明人:陈小川,楼鹏,罗南剑,傅靖贻

发表论文

[1]汤琦,施磊,郑璐,代琴芳,陈小川.禁食时间对昆明小鼠糖耐受和胰岛素分泌的影响[J].中国比较医学杂志,2019,29(10):61-65.

[2]杨丁凡,楼鹏,张然,陈小川.环境热应激对家畜胎盘和胎儿影响的研究进展[J]. 中国草食动物科学,2020,40(5):56-60.

研究生招生

动物科学专业:动物遗传育种与繁殖(专业代码:090501)

五、联系方式

电子信箱:ans@swu.edu.cn

传真:023-68251196

通讯地址:重庆市北碚区天生路2号皇冠买足球的官网 400715